Table 7. X-ray diffraction data processing details for PRWT in complex with GRL-121 or −142.
PRWT + GRL-121 | PRWT + GRL142 | |
---|---|---|
PDB entry | 5TYR | 5TYS |
Resolution range (Å) | 50.0–1.7 | 50.0–2.0 |
Unit cell - a (Å) | 62.56 | 63.13 |
b (Å) | 62.56 | 63.13 |
c (Å) | 82.66 | 82.23 |
α () | 90 | 90 |
β () | 90 | 90 |
γ () | 120 | 120 |
Space group | P61 | P61 |
Solvent content (%) | 54.22 | 54.8 |
No. of unique reflections | 20,171 (994)* | 12,475 (624) |
Mean (I/σ(I)) | 29.05 (3.3) | 26.6 (4.8) |
†Rmerge | 0.09 (0.55) | 0.10 (0.46) |
Data redundancy | 10 (10.1) | 10.2 (9.7) |
Completeness (%) | 100 (100) | 99.9 (100) |
*Values in parentheses are for the highest resolution shell.
†Rmerge = Σ |I - < I > | / Σ I.