Table 1. Summary of physicochemical characterization of dendritic conjugates.
Compound | Molar ratio PTX/Conjugate | Molecular weight (Da) |
Hydro-dynamic diameter
(nm) |
PDI | Diameter by SEM (nm) | Zeta potential (mV) |
---|---|---|---|---|---|---|
dPGS-PTX | ~1 | 12,807 | 45.9 ± 6.7 | 0.693 | 50 ± 20 | −47.1 ± 5.1 |
dPG-PTX | ~1 | 11,207 | 4.2 ± 2.6 | 0.268 | NA | 16.5 ± 4.3 |