Table 6. Coefficients for the CVD and severe adverse event models fit by traditional backwards selection.
| Variable | Hazard ratio (exponentiated coefficient) in CVD event/death model (95% CI) | Hazard ratio (exponentiated coefficient) in serious adverse event model (95% CI) |
|---|---|---|
| Individual terms | ||
| Age | 1.064 (1.048, 1.081) | 1.054 (1.046, 1.062) |
| Female | 1.177 (1.021, 1.356) | |
| Black race | ||
| Hispanic ethnicity | ||
| Systolic blood pressure | 1.002 (0.993, 1.011) | 1.003 (0.999, 1.008) |
| Diastolic blood pressure | 1.005 (0.992, 1.018) | |
| Number of blood pressure medications | 1.205 (1.102, 1.318) | 1.245 (1.129, 1.374) |
| Current smoker | 1.994 (1.532, 2.594) | 1.633 (1.335, 1.998) |
| Former smoker | ||
| Daily aspirin use | ||
| Statin use | ||
| Serum creatinine | 1.603 (1.292, 1.988) | 1.835 (1.566, 2.148) |
| Total cholesterol | 1.003 (1.001, 1.006) | |
| High-density lipoprotein cholesterol | 0.986 (0.979, 0.993) | |
| Triglycerides | ||
| Urine microalbumin/creatinine ratio | 1.001 (1.000, 1.001) | 1.001 (1.001, 1.001) |
| Body mass index | ||
| Intensive treatment arm | 2.123 (0.180, 25.063) | 1.567 (1.156, 2.124) |
| Interaction with intensive treatment arm | ||
| Age | 0.985 (0.962, 1.008) | |
| Systolic blood pressure | 1.010 (0.997, 1.024) | |
| Diastolic blood pressure | 0.981 (0.962, 1.001) | |
| Number of blood pressure medications | 0.911 (0.800, 1.038) |