Figure 8.

EPEC induces the internalization of the basolateral protein Na⁺/K⁺ ATPase and its redistribution to the apical membrane in an EspF-dependent manner. SKCO-15 cells were infected wild-type EPEC, ΔespF, ΔespF/pespFD3 or complemented strain (ΔespF/pespF) for 2–3h, and monolayers immunostained for Na⁺/K⁺ ATPase. Figure shows representative confocal images of three independent experiments. Scale bar, 10 μm.