TABLE 2.

Univariate and Multivariate Analysis Predictors of 12-Month LVEF

Fixed Effect	Beta	SE	p Value
Univariate
Black	−8.65	2.44	0.001
Hypertension	0.102	2.39	0.966
Family history of DCM	−3.21	4.12	0.44
Diabetes	−5.01	3.26	0.16
Breastfeeding	4.94	2.95	0.10
NYHA functional class
II	1.61	3.68	0.66
III	−7.21	4.08	0.08
IV	−3.73	4.29	0.39
ACEi/ARB	3.91	3.15	0.22
Beta-blocker	−1.602	4.17	0.70
Days post-partum at entry	−0.11	0.048	0.02
Baseline LVEF	0.481	0.12	<0.0001
LVEDD	−0.82	0.15	<0.0001
Age	0.127	0.189	0.50
Parity	−0.34	0.94	0.72
SBP, mm Hg	0.016	0.07	0.83
DBP, mm Hg	−0.044	0.102	0.66
Heart rate, beats/min	−0.08	0.07	0.26
BMI	−0.379	0.177	0.04
Multivariate
Baseline LVEF	0.04	0.14	0.79
Baseline LVEDD	−0.66	0.17	<0.0001
Black	−26.03	7.99	0.002
BMI	−0.04	0.15	0.77
Time post-partum	−0.06	0.04	0.18

Significant univariate predictors of LVEF at 12 months included race, baseline LVEF, BMI, and days post-partum to study entry. The beta coefficient represents the slope or the number of units the outcome variable changes with 1-unit change in the predictor variable. These factors were then included in a multivariate model that also included an interaction term for race and baseline LVEF (significant interaction of race baseline LVEF for their impact on 12-month LVEF: beta = 0.72; SE = 0.23; p = 0.002). Only race and LVEDD remain significant in the multivariate analysis.

BMI = body mass index; DCM = dilated cardiomyopathy; other abbreviations as in Table 1.