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. 2017 Oct 17;12(10):e0186625. doi: 10.1371/journal.pone.0186625

Fig 2. Ptpn22 variants do not alter BMDC receptor mediated phagocytosis.

Fig 2

(A-B) Wild type (WT) and Ptpn22-/- derived bone marrow derived dendritic cells (BMDC) were harvested and cell surface CD206 was determined by flow cytometry. (A) Representative CD206 expression profiles on WT (black solid line) and Ptpn22-/- (black dashed line) BMDC. (B) CD206 Geometric Mean Fluorescent Intensity (GMFI). N = 11 independent experiments; bars represent mean ± s.e.m. (C) WT and Ptpn22-/- BMDC were incubated with ovalbumin-AF488 for 0–60 minutes at 37°C prior to CD11c staining. N = 4 independent experiments; line represents the mean ± s.d. (D) WT and Ptpn22R619W BMDC were incubated with ovalbumin-AF488 for 0–60 minutes at 37°C prior to CD11c staining. N = 3 independent experiments; line represents the mean ± s.d.