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. 2017 Oct 17;7:13333. doi: 10.1038/s41598-017-13831-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Top biomarker candidate cluster #7367. (a) Scatter plot of the relative abundance over the different patient groups. The cluster was increased by 222% in AD versus C, by 153% in MCI-AD versus C and by 35% in MCI-S versus C. The p-values were obtained by Mann-Whitney test. (b) ROC curve analysis. The cluster had an AUC of 0.96 for separating AD versus C, an AUC of 0.96 for MCI-AD versus C and an AUC of 0.72 for MCI-S versus C.