Table 2.

Combined analysis including all the sample sets (Helsinki, Tampere, Kuopio, and Oulu) in different subgroups, with number of the c.5791C>T mutation carriers and non-carriers

Study cohort	OR	P	95% CI	N Helsinki wt/mut	N Tampere wt/mut	N Oulu wt/mut	N Kuopio wt/mut
All BC	1.94	0.11	0.87–4.32	2379/12	657/5	1314/9	428/2
Familial BC	2.50	0.10	0.83–7.51	1073/5	–	150/3	–
Unselected BC	1.87	0.14	0.82–4.26	1690/9	657/5	1141/6	428/2
ER+	1.86	0.16	0.78–4.41	1786/9	490/4	432/2	317/1
ER−	2.34	0.14	0.75–7.35	409/3	121/1	108/1	95/0
TNBC	5.14	0.005	1.65–16.0	138/3	67/1	68/1	47/0

BC breast cancer, ER estrogen receptor, TNBC triple-negative breast cancer, wt wild type, mut mutation carrier