Table 3.

Combined analysis including all the sample sets (Helsinki, Tampere, Kuopio, and Oulu) in different subgroups, with the number of the FANCM c.5101C>T and c.5791C>T mutation carriers (combined) and non-carriers

Study cohort	OR	P	95% CI	N Helsinki wt/mut	N Tampere wt/mut	N Oulu wt/mut	N Kuopio wt/mut	N Helsinki controls wt/mut	N Tampere controls wt/mut	N Oulu controls wt/mut	N Kuopio controls wt/mut
All BC	1.86	0.0002	1.32–2.49	2285/81	656/35	1293/30	419/11	1234/21	782/21	498/12	157/1
Familial BC	1.99	0.004	1.24–3.19	1020/38	–	148/5	–	–	–	–	–
Unselected BC	1.77	0.0006	1.28–2.45	1652/58	656/35	1124/23	419/11	–	–	–	–
ER+	1.64	0.005	1.17–2.32	1721/55	480/22	426/8	292/8	–	–	–	–
ER-	2.02	0.004	1.25–3.25	405/16	114/8	108/1	99/2	–	–	–	–
TNBC	3.08	0.00007	1.77–5.35	130/10	60/5	68/1	58/2	–	–	–	–

BC breast cancer, ER estrogen receptor, TNBC triple-negative breast cancer, wt wild type, mut mutation carrier