Table 1.
Patient characteristics of 7227 1-year breast cancer survivors stratified by CVD status
| CVD (n = 193) | No CVD (n = 7034) | |
|---|---|---|
| Follow-upb time in median years (range) | 3 (0–13) | 4 (0–13)* |
| Deceased | 53 (28) | 1077 (15)* |
| Demographics | ||
| Age in median years (range) | 70 (46–91) | 60 (23–102)* |
| Psychological factors | ||
| Anxiety | 45 (23) | 976 (14)* |
| Depression | 15 (8) | 553 (8) |
| Traditional CVD risk factorsa | 118 (61) | 2214 (32)* |
| Hypertension | 106 (55) | 1892 (27)* |
| Hypercholesterolemia | 49 (25) | 810 (12)* |
| Diabetes mellitus | 21 (11) | 398 (6)* |
| Clinical characteristics | ||
| Tumor stage | ||
| 1 | 93 (49) | 3119 (45) |
| 2 | 80 (42) | 2819 (41) |
| 3 | 14 (7) | 761 (11) |
| 4 | 3 (2) | 223 (3) |
| Cancer treatment | ||
| Surgery | 184 (95) | 6677 (95) |
| Chemotherapy | 29 (15) | 2661 (38)* |
| Radiation | 123 (64) | 5042 (72)* |
| Hormone therapy | 72 (37) | 3392 (48)* |
Information is provided in numbers (n) with percentages for categorical variables, whereas follow-up time and age are presented in median years (range). CVD = cardiovascular disease. Psychological and traditional CVD risk factors = being pharmaceutically treated in the 12 months prior to breast cancer diagnosis
aBeing pharmaceutically treated for at least one of the traditional cardiovascular risk factors (hypertension, hypercholesterolemia, diabetes mellitus) during the 12 months prior to cancer diagnosis, yes/no
bFollow-up for a diagnosis of CVD began 12 months after cancer diagnosis, as primary cancer treatment is generally finalized within the first year
*Significant difference (p < 0.05) between those with and without CVD