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. 2017 Sep;36:114–123. doi: 10.1016/j.mito.2017.05.010

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© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 5 — In vivo detection of apoptotic retinal cells using DARC reveals CoQ10/TPGS micelles are significantly neuroprotective in the Morrison's OHT model. [A] Sample DARC image from CoQ10/TPGS treated DA rats exhibiting fewer apoptotic retinal cells (bright spots) than [B] eyes receiving TPGS only micelles or [C] OHT only eyes. [D] CoQ10/TPGS treatment was found to significantly reduce the DARC spot count when quantified by masked observers (one-way ANOVA with Tukey posthoc test, p < 0.05). Results are means ± SE.