Table 1.
Antimicrobial peptides for oncologic indications in ongoing clinical trials.
| Phase | Peptide name | Identifier number | Condition | Administration route |
|---|---|---|---|---|
| I | LL37 | NCT02225366 | Metastatic melanoma | Intratumoral |
| GRN-1201 | NCT02696356 | Solid tumors | Intravenous | |
| LTX-315 | NCT01058616 | Solid tumors | Intravenous | |
| WT-2725 | NCT01621542 | Hematological malignancy and solid tumors | Intravenous | |
| II | SGX942 | NCT02013050 | Head and neck cancer | Intravenous |
| ANG-1005 | NCT02048059 | Breast and brain metastasis | Intravenous | |
| III | ITK-1 | UMIN000011308 | Glioblastoma and prostate cancer | Intravenous |