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HSP90 knockdown impairs CLL tumor cell viability. (a) Efficiency of HSP90 knockdown was assessed by western blot (N =4). Mock, mock transfection; NT, cells were transfected with a pool of non-targeting siRNA. siHSP, cells were transfected with a pool of siRNA against HSP90. GAPDH, western loading control. (b) Effects of siRNA on CLL cell viability (N =6). ***P<0.001.
