Figure 2.

Illustration of graph analysis pipeline. (a) Nodes were defined as the 51 non-adjacent regions from the Yeo 7-network solution atlas (see Figure 1 and Table 2 for a summary of the locations of each node). (b) A total of 51 × 51 partial correlation adjacency matrices were computed from each pairwise correlation, controlling for the signal from all other regions, for resting-state and task-evoked fMRI data separately, and then thresholded and binarized to create an unweighted adjacency matrix such that all correlations above the threshold will be given a value of 1, and below the threshold will be given a value of 0 (see ‘Network Binarization’ in the Supplementary Information for more details). (c) The resulting 51 × 51 binarized matrices were then analyzed as whole-brain graphs for each individual for resting-state and task data separately. Graph metrics were then computed to assess global and local network properties (see ‘Global and Local Graph Metrics’ in the Supplementary Information for more details). Global graph metrics were computed from all 51 regions, resulting in a single value for each individual for each scan. Local graph metrics were computed from the eight ACC regions for each individual for each scan.