Table 1. Phenotypic Assessment of Mothers and Infants Early in Life.

	Prenatal / third trimenon	Perinatal / birth
Exposure to early life stress	Perceived stress (PSS) Prenatal distress (PDQ) Life events (LES) Social support (Soz-U) Socio-demographic data Maternal health risk behavior (eg smoking) Psychosocial risks	Pre- and perinatal complications Perinatal stressors (eg asphyxia, cesarean, preterm birth) Pregnancy and obstetric history (birth weight, gestational age, birth complications)
Maternal mental & physical health	Maternity log data Semi-standardized neuropsychiatric diagnostic interview (M.I.N.I.) Depression screening (EPDS) Anxiety screening (STAI-S, STAI-T, ASQ) Anthropometry Individual & family history of metabolic and other medical disorders
Biological samples	Diurnal saliva cortisol (mother) Saliva sample for genetic and epigenetic analysis (mother / father)	Cord blood for genetic and epigenetic analysis Saliva sample for genetic and epigenetic analysis (infant) Maternal and fetal placenta

Abbreviations: ASQ, anxiety screening questionnaire; EPDS, Edinburgh postnatal depression scale; LES, life experiences survey; M.I.N.I., Mini International Neuropsychiatric Interview; PDQ, prenatal distress questionnaire; PSS, perceived stress scale; SOZ-U, social support questionnaire; STAI-S & STAI-T, state-trait anxiety inventory.