Estimated ratio of apnea-hypopnea index plus one in each group compared to hormone therapy non-users before July 2002, among participants in the Sleep in Midlife Women Study (N= 1,828 observations from 228 subjects), from mixed multivariable regression model with empirical standard errors, adjusting for menopausal stage, age, BMI, neck girth, smoking history, and alcohol use. Product term between hormone therapy use and time period: p<0.01. Madison, WI, 1990–2009.