Table 5.

Univariable analysis of factors potentially associated with increased toxicity with VPP and likelihood of tolerability of vinblastine administered at 3.00 mg/m² weekly

	Grade 3 neutropenia	Grade 4 neutropenia	Increased risk of dose reduction	Decreased tolerability of vinblastine 3.00 mg/m2 weekly administered once
Age	0.042 *	0.872	0.074*	0.179*
Weight	0.172*	0.748	0.127*	0.155*
Sex	0.230	0.604	0.152*	0.446
Neutered	0.128*	0.033 *	1.000	0.648
Patnaik Grade (2 vs. 3)	0.249	1.000	0.362	0.41
Kiupel (High vs. Low)	0.561	1.000	0.459	0.699
Margin (incomplete)	1.000	0.126*	0.696	0.244
MI (>5)	0.156*	1.000	0.074*	0.185*
Radiation therapy	1.000	0.048 *	1.000	1.000

Representative P‐values are shown (Fisher's exact test). *variables selected for subsequent multi‐variable analysis. Values in bold indicate P < 0.05.