Table 2.
Status of drug-resistant tuberculosis in India
| Drug resistance | n | Prevalence estimate (95% CI) | Heterogeneity test (I2) |
|---|---|---|---|
| 1995 to 2015 | |||
| Any drug-resistance | 61 | 42.6% (37.2; 48.0) | 14.4 |
| Multidrug resistance | 73 | 23.3% (20.5; 26.1) | 69.2 |
| Previously treated | 37 | 33.7% (27.9; 39.5) | 29.0 |
| Newly diagnosed | 30 | 4.8% (3.7; 5.9) | 79.3 |
| Mono-drug resistance | |||
| Isoniazid | 53 | 7.2% (5.9; 8.4) | 72.5 |
| Streptomycin | 40 | 6.7% (5.4; 8.0) | 67.4 |
| Rifampicin | 42 | 4.6% (3.8; 5.5) | 91.3 |
| Ethambutol | 31 | 1.6% (1.2; 2.0) | 92.0 |
| Decade 1: 1995 to 2005 | |||
| Any drug-resistance | 25 | 37.7% (29.0; 46.4) | 10.5 |
| Multidrug resistance | 24 | 14.9% (11.0; 18.7) | 68.4 |
| Previously treated | 13 | 29.8% (20.7; 39.0) | 45.0 |
| Newly diagnosed | 13 | 4.1% (2.7; 5.6) | 70.2 |
| Mono-drug resistance | |||
| Isoniazid | 21 | 8.6% (6.2; 10.9) | 83.7 |
| Streptomycin | 18 | 6.7% (5.0; 8.5) | 81.1 |
| Rifampicin | 15 | 3.6% (2.5; 4.7) | 94.7 |
| Ethambutol | 13 | 1.9% (1.2; 2.6) | 96.1 |
| Decade 2: 2006 to 2015 | |||
| Any drug-resistance | 36 | 46.1% (39.0; 53.2) | 9.1 |
| Multidrug resistance | 49 | 27.9% (23.8; 32.1) | 57.1 |
| Previously treated | 24 | 35.8% (29.2; 42.4) | 36.3 |
| Newly diagnosed | 17 | 5.6% (3.8; 7.4) | 82.1 |
| Mono-drug resistance | |||
| Streptomycin | 22 | 6.8% (4.8; 8.8) | 28.7 |
| Isoniazid | 32 | 6.2% (5.0; 7.5) | 24.9 |
| Rifampicin | 27 | 5.1% (3.7; 6.6) | 84.3 |
| Ethambutol | 18 | 1.7% (1.0; 2.3) | 45.2 |
CI Confidence interval, n Number of studies