Table 3.

The prevalence and concentrations of pepsin in saliva for controls and two groups of patients

Parameters	Controls (n = 35)	Non-GERD (n = 128)	GERD (n = 122)	P
Prevalence of positive samples (%)	29.5	32.3	62.0	<0.001
Proportion of subjects having at least one positive samples (%)	42.9	53.1	91.0	<0.001
Proportion of subjects having all three positive samples (%)	11.4	10.9	13.1	0.864
Concentrations of salivary pepsin (ng/mL), median (IQR)	0 (0–25)	18.5 (0–59.75)	153.3 (70–365.8)	<0.001

GERD gastro-esophageal reflux disease, IQR interquartile rang