Table 1.
Instrument | All patients | ITT patients | ||
---|---|---|---|---|
Mean change | p-value | Mean change | p-value | |
Short Form-36v2 Health Surveya | ||||
Physical Functioning | 6.7 | <0.0001 | 8.0 | <0.0001 |
Role-Physical | 7.7 | <0.0001 | 9.1 | <0.0001 |
Bodily Pain | 9.8 | <0.0001 | 11.6 | <0.0001 |
General Health | 2.3 | <0.0001 | 3.1 | <0.0001 |
Vitality | 4.6 | <0.0001 | 5.8 | <0.0001 |
Social Functioning | 5.0 | <0.0001 | 7.0 | <0.0001 |
Role-Emotional | 3.4 | <0.0001 | 4.7 | <0.0001 |
Mental Health | 2.3 | <0.0001 | 3.5 | <0.0001 |
Physical Component Score | 8.2 | <0.0001 | 9.6 | <0.0001 |
Mental Component Score | 1.6 | 0.0026 | 2.9 | <0.0001 |
EuroQol-5 Dimensions 3-Levelb | ||||
Summary Index | 0.12 | <0.0001 | 0.14 | <0.0001 |
Visual Analog Scale | 8.16 | <0.0001 | 9.84 | <0.0001 |
Work Productivity and Activity Impairment Questionnaire: Specific Health Problemc | ||||
Percentage work time missed due to low back pain | −1.3 | 0.3822 | −4.9 | 0.0017 |
Percentage impairment while working due to low back pain | −22.4 | <0.0001 | −25.9 | <0.0001 |
Percentage overall work impairment due to low back pain | −21.6 | <0.0001 | −26.9 | <0.0001 |
Percentage activity impairment due to low back pain | −27.2 | <0.0001 | −32.0 | <0.0001 |
ITT intent to treat
aHigher scores indicate a better health-related quality of life. bHigher scores indicate a better health. cHigher scores indicate less productivity/greater impairment