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. Author manuscript; available in PMC: 2017 Oct 18.
Published in final edited form as: Breast Cancer Res Treat. 2016 Oct 18;160(3):447–456. doi: 10.1007/s10549-016-4021-7

Fig. 3.

Fig. 3

Breakpoint determination. a PALB2 exon 13 duplication confirmation by long-range PCR. An extra band of approximately 4–6 kb in size was detected in the proband’s blood DNA, which is absent in the negative control sample. b Localization of breakpoint. Electropherogram showing the breakpoint sequence. c Sequence alignment in the breakpoint region showing the 32-bp perfect identity between the intron 12 and 3′-UTR of PALB2