FIG 4 .

Cryo-EM image reconstruction of the 2D3/MNV complex fitted with the atomic models of the MNV P domain dimer and two of the MAb 2D3 Fabs. (A) Surface rendering of the entire virus colored according to the particle radius. (B) Center section of the same structure. The Fab constant domains are shown in dark blue, the variable domain in cyan, and the P domain in yellow/orange. The shell domain is orange, and the RNA interior is purple. (C) A stereo image of the Situs fitted components corresponding to the cryo-EM density data. The heavy chains are shown in green, the light chains in yellow, and the two conformations of the P domain, A and B, in red and blue, respectively.