TABLE 3.

DTI Measures Predict Changes in Ham-D-17 Over 1 Year Among 13 Mild TBI Participants

Regions of Interest	Baseline Association: b (95% CI); p	Longitudinal Association b Time (95% CI); p
FA superior temporal gyrus, left	3.09 (−3.72, 9.91); 0.374	−0.80 (−1.56, −0.03); 0.042
FA middle temporal gyrus, left	−1.05 (−6.35, 4.26); 0.70	−0.80 (−1.45, −0.15); 0.016
MD superior longitudinal fasciculus, right	−0.91 (−4.43, 2.61); 0.61	0.50 (0.12, 0.87); 0.009
MD superior longitudinal fasciculus, left	0.04 (−4.35, 4.43); 0.99	−0.51 (−1.02, −0.01); 0.045
MD superior frontal gyrus, right	−0.32 (−2.77, 2.12); 0.80	0.26 (−0.02, 0.54); 0.066
MD superior frontal WM, right	0.27 (−3.72, 4.26); 0.89	0.40 (−0.03, 0.83); 0.07
MD inferior frontal WM, right	−0.38 (−4.27, 3.51); 0.85	0.66 (0.21, 1.10); 0.004
MD superior temporal WM, right	−0.56 (−4.48, 3.35); 0.78	0.52 (0.10, 0.95); 0.016
MD middle temporal WM, right	−1.73 (−7.54, 4.09); 0.56	0.54 (−0.07, 1.15); 0.08

CI: confidence interval; FA: fractional anisotropy; MD: mean diffusivity; WM: white matter.

b: association between the region of interest and FA or MD at baseline.

b: *Time: baseline FA or MD predicting change over 1 year (4 visits), using linear mixed models.