Table 3.
Determination of significant neuroprotective factors associated with risk of cognitive impairment.
| Selected neuroprotective factors | B | exp(B) | 95% confidence interval | p | ||
|---|---|---|---|---|---|---|
| Upper | Lower | |||||
| MCI | Serum Vitamin D (nmol/L) | −0.05 | 0.96 | 0.92 | 0.99 | <0.05a |
| Telomere Length (kb/diploid genome) | −0.03 | 0.97 | 0.95 | 0.99 | <0.001a | |
| BDNF (nmol/L) | −0.67 | 0.51 | 0.30 | 0.88 | <0.05b | |
| UA | Serum Vitamin D (nmol/L) | −0.02 | 0.98 | 0.94 | 1.02 | >0.05 |
| Telomere Length (kb/diploid genome) | −0.03 | 0.98 | 0.96 | 0.99 | <0.01a | |
| BDNF (nmol/L) | −0.59 | 0.56 | 0.33 | 0.93 | <0.05b | |
BDNF: brain-derived neurotrophic factor; SA: successful ageing; UA: usual ageing; MCI: mild cognitive impairment. Multinomial Logistic Regression with reference group is successful ageing. aSignificant at p < 0.05 after being controlled for age, gender, educational level, and smoking status. bSignificant at p < 0.05 after being controlled for confounding factors: age, gender, educational level, smoking, physical function, and depressive symptoms.