Skip to main content
. Author manuscript; available in PMC: 2017 Oct 18.
Published in final edited form as: Cell Rep. 2017 Jun 20;19(12):2572–2585. doi: 10.1016/j.celrep.2017.05.079

Figure 3. Piezo1 channels function as low-pass filters of square pulse pressure stimuli.

Figure 3

(A) Repetitive square pulse pressure protocols (30 ms at −50 mmHg, varying times at +5 mmHg) and representative raw currents from HEK293t cells transiently transfected with Piezo1. Scale bars (25 pA, 500 ms) apply to all traces except 10 Hz inset (20 pA, 50 ms). (B) Mean amplitudes of the ‘first peak’ (red circles) and ‘last peak’ (blue circles) currents, normalized to the peak amplitude of ‘step1’. All data are mean ± s.e.m. N = 7–11 cells per frequency. See also Figures S1, S5.