Figure 5.

Unbiased, multidimensional tSNE clustering analysis of first-trimester decidual macrophages from uninfected and P. gingivalis infected macaques (A) shows a greater proportion of MIP1a⁺ cells and a lower proportion of CD206⁺ cells with P. gingivalis infection compared with controls. Each dot represents an individual cell, colored by marker expression as shown in the corresponding table below each graph. (B) Manual gating with FlowJo v10.3 confirms a decrease in CD206⁺ macrophages. Value indicates percentage of CD45⁺ cells.

Pg = infected with P. gingivalis; Control = uninfected, gestational age-matched control.