Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 1;32(7):247–257. doi: 10.1089/cbr.2017.2253

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright 2017, Mary Ann Liebert, Inc.

PMC Copyright notice

FIG. 4. — PET imaging and terminal tissue analysis of Dox-⁶⁴Cu-DOTA-LNP in NOD-SCID mice bearing PSMA-positive LNCap prostate tumors. (A) PET imaging of ⁶⁴Cu-DOTA-Dox-LNP. Dox-⁶⁴Cu-DOTA-LNP was injected into two male NOD/SCID mice bearing LnCap tumors and PET imaged at 4 and 20 hours. (B) Terminal tissue data of Dox-⁶⁴Cu-DOTA-LNP. After the final PET image was acquired, mice were euthanized, tissues weighed and counted for radioactivity for biodistribution analysis. The data are expressed for the two individual mice as % ID/g for major organs at the terminal time point of 20 hours. Dox, doxorubicin; LNP, lipid nanoparticle; NOD/SCID, non-obese diabetic severe combined immune deficiency; PET, positron emission tomography; PSMA, prostate-specific membrane antigen.