Table 1. Participant characteristics according to presence or absence of all-cause mortality and CVD hospitalization end-points.
All-cause mortality | CHD hospitalization | Stroke hospitalization | |||||
---|---|---|---|---|---|---|---|
Overall (N = 51,462) | No (N = 50,543) | Yes (N = 919) | No (N = 49,796) | Yes (N = 1666) | No (N = 49,952) | Yes (N = 1510) | |
Age, mean years (SD) | 62.65 (12.07) | 62.45 (12.02) | 73.37 (10.21) | 62.5 (12.1) | 67.19 (10.36) | 62.41 (12.05) | 70.44 (9.89) |
Men, % | 47.59 | 47.26 | 65.61 | 47.07 | 63.09 | 47.35 | 55.56 |
BMI, kg/m2, mean (SD) | 29.53 (4.83) | 29.54 (4.83) | 29.19 (4.89) | 29.52 (4.84) | 29.87 (4.59) | 29.54 (4.84) | 29.29 (4.55) |
Obesity, % | 42.09 | 42.12 | 40.48 | 41.99 | 44.90 | 42.15 | 40.07 |
Former smoking, % | 20.78 | 20.66 | 27.53 | 20.39 | 32.59 | 20.67 | 24.57 |
Current smoking, % | 22.22 | 22.26 | 20.46 | 22.39 | 17.29 | 22.35 | 17.95 |
Diabetes, % | 37.20 | 36.88 | 54.41 | 36.62 | 54.44 | 36.76 | 51.59 |
Glucose lowering medication, % | 19.39 | 19.51 | 12.95 | 19.00 | 31.15 | 19.14 | 27.95 |
Systolic blood pressure, mean mmHg (SD) | 136.24 (18.19) | 136.17 (18.16) | 140.19 (19.64) | 136.11 (18.14) | 140.32 (19.26) | 136.11 (18.14) | 140.75 (19.17) |
Diastolic blood pressure, mean mmHg (SD) | 79.36 (10.85) | 79.41 (10.84) | 76.71 (10.83) | 79.4 (10.83) | 78.4 (11.37) | 79.39 (10.83) | 78.52 (11.41) |
Hypertension, % | 78.98 | 78.78 | 90.42 | 78.55 | 92.14 | 78.59 | 92.05 |
Antihypertensive medication, % | 43.56 | 43.95 | 22.20 | 43.10 | 57.20 | 43.27 | 53.18 |
Chronic kidney disease, % | 15.01 | 14.69 | 32.43 | 14.69 | 24.31 | 14.66 | 26.36 |
Total cholesterol, mean mg/dL (SD) | 211.01 (40.97) | 211.26 (40.93) | 197.58 (41.02) | 211.35 (40.84) | 201.02 (43.61) | 211.25 (40.9) | 203.12 (42.49) |
HDL-cholesterol, mean mg/dL (SD) | 52.7 (13.94) | 52.74 (13.93) | 50.55 (13.98) | 52.83 (13.94) | 48.86 (13.2) | 52.76 (13.95) | 50.8 (13.38) |
Non-HDL-cholesterol, mean mg/dL (SD) | 158.31 (39.41) | 158.52 (39.39) | 147.04 (38.7) | 158.52 (39.3) | 152.16 (42) | 158.49 (39.36) | 152.32 (40.49) |
LDL-cholesterol, mean mg/dL (SD) | 126.2 (34.33) | 126.36 (34.31) | 117.62 (34.37) | 126.4 (34.25) | 120.06 (36.16) | 126.34 (34.3) | 121.47 (35.03) |
Triglycerides, mean mg/dL (SD) | 149.69 (100.01) | 149.89 (100.29) | 138.46 (82.37) | 149.47 (100.13) | 156.38 (96.15) | 149.86 (100.51) | 143.95 (81.65) |
Ratio total/HDL-cholesterol | 4.22 (1.2) | 4.22 (1.2) | 4.12 (1.17) | 4.22 (1.2) | 4.34 (1.27) | 4.22 (1.2) | 4.2 (1.19) |
Ratio triglycerides/HDL-cholesterol | 3.26 (3.01) | 3.26 (3.02) | 3.11 (2.69) | 3.25 (3.01) | 3.63 (3.07) | 3.26 (3.03) | 3.18 (2.36) |
Dyslipidemia, % | 88.23 | 88.39 | 79.22 | 88.04 | 93.76 | 88.20 | 89.01 |
Lipid lowering medication, % | 30.28 | 30.60 | 12.73 | 29.80 | 44.60 | 30.09 | 36.76 |
CVD: cardiovascular disease; CHD: coronary heart disease; SD: statistical deviation; BMI: body mass index; HDL: High density lipoprotein; LDL: low density lipoprotein