Figure 3.

Silencing EDIL3 expression inhibits HREC tube formation in vitro. HRECs were transfected with siEDIL3 or scramble siRNA and a tube formation assay was performed. Representative photomicrographs of formed capillary-like structures in (A) control (B) scramble and (C) siEDIL3 groups. Scale bars, 200 µm. (D) Silencing EDIL3 expression significantly impaired tube formation in HRECs. *P<0.05 vs. control and scramble groups. EDIL3, epidermal growth factor-like repeat and discoidin I-like domain-containing protein 3; HRECs, human retinal endothelial cells; si, small interfering.