Figure 5.

Effect of curcumin on nuclear NF-κB expression at the whole cortex, penumbra and core area as detected by immunohistochemistry. (A) Positive NF-κB nuclear staining was visualized in brown color and indicated by white arrows. Scale bar, 100 µm. (B) The number of cells with positive nuclear NF-κB staining was quantified. *P<0.05, **P≤0.01 and ^#P≤0.0001, with comparisons indicated by brackets. NF, nuclear factor; MCAO, middle cerebral artery occlusion; CUR, curcumin; CORN, corn oil (vehicle control); ns, not significant.