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Effects of TGF-β1, SB203580, PD98059, SP600125 and OMT on (A) type I and (B) type III collagen protein expression in CFBs as examined by western blotting. Data are expressed as the mean ± standard error of the mean (n=3). ##P<0.01 vs. control; **P<0.01 vs. TGF-β1 group. TGF-β1, transforming growth factor-β1; OMT, oxymatrine; CFBs, cardiac fibroblasts; Coll I, type I collagen; Coll III, type III collagen; L, low-dose; M, medium-dose; H, high-dose.
