Table II.
Expression of miR-136-5p and clinicopathological parameters in HCC in the Cancer Genome Atlas.
| lg(miR-136-5p) expression | ||||
|---|---|---|---|---|
| Clinicopathological features | n | Mean ± standard deviation | t | P-value |
| Tissue | ||||
| Adjacent non-cancerous liver | 50 | 2.4517±0.2036 | 8.808 | <0.0011 |
| HCC | 215 | 2.0279±0.5652 | ||
| Age | ||||
| <60 | 103 | 2.1058±0.5637 | 2.000 | 0.047 |
| ≥60 | 111 | 1.9520±0.5602 | ||
| Gender | ||||
| Male | 156 | 1.9845±0.5384 | 1.842 | 0.067 |
| Female | 59 | 2.1427±0.6209 | ||
| AJCC pathologic T | ||||
| T0 TX | 1 | 2.3263 | F=0.231a | 0.749 |
| T1 | 130 | 2.0382±0.5771 | ||
| T2-T4 | 82 | 2.0040±0.5532 | ||
| AJCC pathologic N | ||||
| N0 | 151 | 2.0358±0.5933 | 0.314 | 0.745 |
| NX | 64 | 2.0093±0.4966 | ||
| AJCC pathologic M | ||||
| M0 | 156 | 2.0428±0.6010 | F=0.355a | 0.702 |
| M1 | 1 | 1.6721 | ||
| MX | 58 | 1.9939±0.4617 | ||
| Grade | ||||
| I~II | 20 | 2.1286±0.5371 | 0.871 | 0.631 |
| III~IV | 4 | 2.2691±0.4566 | ||
| Cirrhosis | ||||
| − | 203 | 2.0335±0.5514 | 1.132 | 0.259 |
| + | 3 | 1.6682±0.8406 | ||
| Pathologic stage | ||||
| I~II | 175 | 2.0404±0.5639 | 1.576 | 0.117 |
| III~IV | 27 | 1.8546±0.6092 | ||
| Vaso-invasion | ||||
| − | 129 | 2.0159±0.5331 | 0.076 | 0.939 |
| + | 72 | 2.0223±0.6249 | ||
a
One-way analysis of variance analysis was performed. HCC, hepatocellular carcinoma.