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. 2017 Aug 16;16(4):5241–5248. doi: 10.3892/mmr.2017.7257

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Inhibition of miR-130a inhibits CRC cell proliferation, migration and invasion. (A) Reverse transcription-quantitative polymerase chain reaction was performed to determine miR-130a expression levels in SW620 and HT29 cells after transfection with miR-130a or NC inhibitors. (B) MTT assay was used to investigate the effect of the miR-130a inhibitor on SW620 and HT29 cell proliferation. (C) The migration and invasion capacity of SW620 and HT29 cells transfected with miR-130a inhibitor or NC inhibitor was evaluated by migration and invasion assay. Data are expressed as the mean ± standard deviation. *P<0.05 vs. NC inhibitor. CRC, colorectal cancer; miR, microRNA; NC, negative control; OD, optical density.