Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 18;16(4):5151–5156. doi: 10.3892/mmr.2017.7286

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — AKAP2 activate β-catenin/TCF signaling in ovarian cancer cells. (A) AKAP2 activated Topflash, the reporter gene for β-catenin/TCF signaling, in OVCAR3 cells. (B) Knockdown of AKAP2 expression inhibited the expression of Snail, c-Myc and N-cadherin in OVCAR3 and OVCA433 cells. (C) ICG001, an inhibitor of β-catenin/TCF signaling, reversed the promoting effects of AKAP2 on the growth of OVCAR3 cells in the crystal violet assay. ^##P≤0.01 vs. pcDNA3.1 + Wnt3a. AKAP2, A-kinase anchoring protein 2; TCF, T cell factor; si, small interfering RNA; con, control.