Table 1.
Early onset sepsis | ||||
Controls (n = 20) | Blood culture negative (n = 65) | Blood culture positive (n = 6) | P value | |
Pregnancy, n (%) | ||||
Complications* | 3 (15) | 16 (25) | 1 (17) | 0.63 |
Chorioamnionitis† | 0 | 18 (28) | 0 | |
Mode of delivery, n (%) | ||||
Vaginal | 12 (60) | 46 (75) | 4 (67) | 0.54 |
Caesarean | 8 (40) | 19 (25) | 2 (33) | |
Sex, n (%) | ||||
Male | 9 (45) | 29 (45) | 5 (83) | 0.19 |
Female | 11 (55) | 36 (55) | 1 (17) | |
Ethnicity, n (%) | ||||
Maroon and Creole | 12 (60) | 44 (68) | 4 (67) | |
Hindo-Surinamese | 3 (15) | 14 (21) | 1 (17) | 0.61 |
Other‡ | 5 (25) | 7 (11) | 1 (17) | |
Gestational age, n (%) (weeks) | ||||
34–37 | 1 (5) | 22 (34) | 0 | |
37–40 | 14 (70) | 30 (46) | 4 (67) | 0.06 |
≥40 | 5 (25) | 13 (20) | 2 (33) | |
Apgar score, n (%) | ||||
<5 | 0 | 5 (8) | 2 (33) | 0.03 |
Birth weight, median (IQR) (g) | 3,130 (700) | 2,840 (835) | 3,500 (906) | 0.02 |
Age at presentation, n (%) (h) | ||||
<24 | 4 (20) | 43 (66) | 2 (33) | |
24–48 | 7 (35) | 13 (20) | 1 (17) | <0.01 |
48–72 | 9 (45) | 9 (14) | 3 (50) | |
Clinical course (at 48–72 h), n (%) | ||||
CPAP | 0 | 9 (14) | 0 | |
Mechanical ventilation | 0 | 7 (11) | 2 (33) | |
Cardiotonics | 0 | 5 (8) | 1 (17) | <0.001 |
Mortality | 0 | 3 (5) | 2 (33) |
*Presence of pregnancy-induced hypertension, preeclampsia, or diabetes mellitus.
†Defined as intrapartum fever or administration of antibiotics.
‡Includes: Javanese, Chinese, Caucasian, and Amerindian.
CPAP indicates continuous positive airway pressure; IQR, interquartile range; N/A, not applicable.