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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: J Biophotonics. 2017 Apr 18;10(12):1714–1722. doi: 10.1002/jbio.201600314

Figure 3.

Figure 3

Simulated fitting of angular scattering spectra from low-index nuclei, using a high-index lookup table. (Top) A sample angular spectrum, m < 1, along with its best fit, m > 1. In this case, the nuclear diameter is correctly determined to be 12.7 μm. (Middle left) All simulations on the parameter space. Size accuracy is limited for individual measurements. (Middle Right) Average fit for groups of N=7 spectra with a size standard deviation of 10% from the test diameter. (Bottom) Bland-Altman plot for the size-averaged fits. Half of the error comes from a systematic offset of 0.691 μm, which does not affect diagnostic accuracy. Ignoring the offset, the remaining error has standard deviation of 0.689 μm. Red lines indicate 95% limits of agreement, or ±1.96 times the standard deviation of the error. All simulations were performed at 792.1 nm, the measured center wavelength of a benchtop a/LCI system in our lab.