Fig. 3.

Network of pathovar specific enriched functions and transcription factors. a Network legend for the figure. b Graphical representation of the functional processes predicted to be commonly and differentially modulated by orthologous transcription factors (TFs) in extra-intestinal and gastro-intestinal pathovars. c A specific example, enlarged from b demonstrating the loss in gastro-intestinal and extra-intestinal pathovars of regulatory relationships between cpxR and genes involved in the negative regulation of apoptosis and chemotaxis respectively. TF transcription factor, TFBS transcription factor binding site