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. 2017 Oct 18;7:13462. doi: 10.1038/s41598-017-13857-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The location of the pemIK-Scar operon in S. carnosus, S. condimenti and S. simulans. The cassette containing the pemIK operon in the chromosomal sequence of S. carnosus TM300 or putative chromosomal contigs. White arrows indicate sequences that encode hypothetical proteins, and coloured arrows indicate the following genes: alkyl hydroperoxide reductase large subunit, ahpF, sky blue; putative phosphatase, olive; putative lipoprotein, light green; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase or related deacylase, blue; fructose-2,6-bisphosphatase, mutase, sky blue; putative protein with monooxygenase domain, yellow; S18 ribosomal protein, green; putative DNA-binding protein, dbp, dark grey; S6 ribosomal protein, green; thermonuclease, magenta; pemIK locus, red; putative ornithine carbamoyltransferase, argF, beige; putative oxidoreductase, pale red; putative surface protease; pale green; putative 5-amino-6-(5-phosphoribosylamino)uracil reductase, ribD, sea blue; putative translation factor of GTPase activity, pale purple; putative mechano-sensitive ion channel, ion channel, mscS, dark brown; transporters, genes involved in haem metabolism, isdC, hbp, light grey; YSIRK signal peptidase, purple; and a putative LPXTG-anchored surface protein, light grey.