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. 2017 Oct 18;7:13424. doi: 10.1038/s41598-017-13949-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Long-term intake of P-BBG diet prevents body weight gain without altering glucose tolerance. (A) Time-dependent effects of diet supplemented with P-BBG (n = 15) or regular pasta (Control; n = 15) on murine body weight. (B) Time-dependent changes in food intake in both experimental groups. (C) Levels of blood glicemia before (T0) and after intraperitoneal bolus of glucose solution (1 mg/g body weight) at baseline in P-BBG (n = 15) and Control group (n = 15). (D) Levels of blood glicemia before (T0) and after intraperitoneal bolus of glucose solution (1 mg/g body weight) after 5 weeks of experimental feeding in both experimental groups. P-BBG: low fat diet supplemented with barley beta-D-glucan enriched pasta (3 g/100 g of dry weight). All measurements are mean ± SD. *p < 0.05 vs. 0 weeks; § p < 0.05 vs. Control.