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. 2017 Oct 18;7:13442. doi: 10.1038/s41598-017-13880-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Short LMB treatment of hepG2 cells in culture while internalizing natLDL and oxLDL. (a) Response to a LMB treatment upon internalization of natLDL and oxLDL (Dil) in hepG2 cells. (b) Cell viability measured by MTT assays. (c) ROS production by LMB treated hepG2 cells while in the presence of natLDL and oxLDL. (d) Western-blot analysis of proteins c-Jun, c-Myc, and β-adaptin present in hepG2 cells while treated with LMB in the presence of natLDL or oxLDL (e) Immunoprecipitation assay to evaluate the interaction between c-Myc and β-adaptin in hepG2 cells treated with LMB in the presence of natLDL or oxLDL. Mean values are presented (n = 6, X ± SD) *p < 0.05, **p < 0.01.