Table 3.

Comparative gene expression between zones of growth cartilage: separate P values for early and late specimens.

	Early (n = 8)		Late (n = 14)
Gene	H vs R1	H vs P1	H vs R	H vs P
Genes up-regulated in the hypertrophic zone:
ATP6V0D2	P = 0.004	P = 0.045	P = 0.002	P = 0.008
BAK1	P = 0.004	ns2	P = 0.005	P = 0.004
DDX5	P = 0.006	P = 0.045	P = 0.001	P = 0.001
GNB1	P = 0.045	P = 0.017	P = 0.03	P = 0.018
PIP4K2A	P = 0.001	P = 0.009	P = 0.001	P = 0.001
RAP1B	P = 0.001	ns	P = 0.001	P = 0.001
RPS7	P = 0.005	ns	P = 0.014	P = 0.035
SRSF3	P = 0.001	P = 0.013	P = 0.001	P = 0.001
SUB1	P = 0.001	P = 0.038	P = 0.001	P = 0.001
TMSB4	P = 0.001	P = 0.012	P = 0.004	P = 0.007
TPI1	P = 0.001	P = 0.006	P = 0.003	P = 0.001
WSB2	P = 0.001	P = 0.021	P = 0.001	P = 0.024
Genes down-regulated in the hypertrophic zone:
FOXA3	P = 0.001	ns	P = 0.049	ns
SERPINA1	P = 0.001	P = 0.002	P = 0.001	P = 0.001

1: R - reserve zone; P - zone of proliferative chondrocytes; H - zone of hypertrophic chondrocytes.

2: ns - not significantly different.