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. 2017 Oct 12;17:115–123. doi: 10.1016/j.nicl.2017.10.013

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 4 — A hypothetical illustration of altered subcortical FC with the cortex and the changes after CBTi in patients with PI. Between the cortex and the BG, weaker FC compared to GS, was increased after CBTi. Between the cortex and the thalamus, stronger FC compared to GS, was decreased after CBTi. Between the cortex and the hippocampus, weaker FC compared to GS, was increased after CBTi. The connection between the BG and the thalamus was not explored in the present study, but presented in the illustration based on the cortico-striato-thalamo-cortical circuit. Broken lines represent weaker or decreased FC compared to GS or pre-CBTi, respectively. Thick solid lines represent stronger or increased FC compared to GS or pre-CBTi, respectively. Abbrevations: FC, functional connectivity; CBTi, cognitive-behavioral therapy for insomnia; BG, basal ganglia; GS, good sleepers.