Table 3. Causes of Death for Patients With Any Synucleinopathy, and for PD, Compared With Referent Participants.
| Primary Cause of Death | No. (%) | |
|---|---|---|
| Patients (n = 311)a |
Referent Participants (n = 216)a |
|
| Synucleinopathies | ||
| Neurodegenerative disease | 98 (31.5) | 25 (11.6) |
| Cardiovascular events | 49 (15.8) | 55 (25.5) |
| Respiratory failure/pneumonia | 48 (15.4) | 32 (14.8) |
| Others | 29 (9.3) | 19 (8.8) |
| Aspiration | 25 (8.1) | 7 (3.2) |
| Cancers | 22 (7.1) | 39 (18.1) |
| Sepsis | 17 (5.5) | 9 (4.2) |
| Stroke/hemorrhages | 11 (3.5) | 16 (7.4) |
| Traumas (including falls) | 7 (2.3) | 8 (3.7) |
| Renal failure | 5 (1.6) | 6 (2.8) |
|
Patients (n = 172) |
Referent Participants (n = 130) |
|
| Parkinson Disease | ||
| Neurodegenerative disease | 44 (25.6) | 10 (7.7) |
| Cardiovascular events | 28 (16.3) | 34 (26.2) |
| Respiratory failure/pneumonia | 23 (13.4) | 17 (13.1) |
| Cancers | 20 (11.6) | 29 (22.3) |
| Others | 19 (11.1) | 11 (8.5) |
| Aspiration | 15 (8.7) | 4 (3.1) |
| Stroke/hemorrhages | 9 (5.2) | 11 (8.5) |
| Traumas (including falls) | 5 (2.9) | 6 (4.6) |
| Sepsis | 5 (2.9) | 5 (3.8) |
| Renal failure | 4 (2.3) | 3 (2.3) |
Abbreviation: PD, Parkinson disease.
a
Death certificates were not available for 5 patients and 4 referent participants. These persons are not included in this table.