Table 2.

Fixed effects for model predicting verbal memory and motor change

Parameter, effects	FCSRT				UPDRS-III
	B	SE	95% CI	p-value	B	SE	95% CI	p-value
Intercept	26.86	0.99	24.92, 28.79	<0.01	9.71	1.23	7.30, 12.12	<0.01
Age	−0.31	0.04	−0.39, −0.23	<0.01	0.38	0.06	0.26, 0.50	<0.01
Gender	2.09	0.45	1.19, 2.96	<0.01	−1.20	0.58	−2.34, −0.06	0.04
Race	−1.61	0.50	0.46, 2.31	<0.01	0.60	0.60	−0.58, 1.78	0.32
Education	0.16	0.06	0.03, 0.28	0.01	−0.10	0.07	−0.24, 0.03	0.20
GBA status	−0.13	1.15	−2.40, 2.11	0.91	−1.49	1.04	−3.53, 0.55	0.15
Time	−0.23	0.06	−0.36, −0.10	<0.01	0.59	0.10	0.39, 0.79	<0.01
Age × time	−0.03	0.01	−0.05, −0.02	<0.01	0.05	0.01	0.03, 0.06	<0.01
Gender × time	−0.18	0.08	−0.35, −0.02	0.03	0.11	0.12	−0.13, 0.35	0.36
GBA status × time	−0.42	0.20	−0.80, −0.03	0.03	0.17	0.29	−0.40, 0.74	0.56

Note: the model for FCRST is a single model with all listed variables as covariates. The model for UPDRS-III is a single model with all listed variables as covariates. The effect ‘time’ indicates the rate of change, that is, slope, in points per year. The interaction terms with time measure the effect of baseline age, gender, and genetic status, respectively, on the rate of change in FCSRT and UPDRS-III.

Key: FCSRT, free and cued selective reminding test; UPDRS-III, unified Parkinson’s disease rating scale motor section.