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. 2017 Aug 25;14(5):4118–4124. doi: 10.3892/etm.2017.5034

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Copyright: © Wen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — In vivo 1H MR spectroscopic analysis of brain metabolites. (A) Representative spectra obtained and close-up views of the spectral region encompassing the Cho, Cr and NAA peaks for the control, 6, 12 and 24 h groups. The peaks used in the calculation of the ratios are markedly visible at 3.03 and 2.02 ppm for total Cr and NAA, respectively. (B) Average values ± SEM of the peak value ratios of NAA to total Cr in each group. We observed a significant reduction in NAA/Cr ratio. A statistically significant difference between the indicated group and the control group (*p<0.05). A statistically significant difference between the indicated group and the 6 h group (^#p<0.05). MR, magnetic resonance; Cho, choline; NAA, N-acetylaspartate.