Extended Data Table 2.
Mutations of the BRCC tumour samples
| Gene | Alteration | Primary Kidney (Foundation Medicine) | Ovary Metastasis (IMPACT) | Ovary Metastasis PDX (IMPACT) |
|---|---|---|---|---|
| FBXW7 | R505C | X | X | X |
| BRAF | D594N | X | X | |
| BRAF | G466A | X | X | X |
| FLT3 | V194M | X | X | |
| JAK3 | V722I | X | X | |
| CDH1 | R749L | X | X | X |
| TBX3 | H106Y | X | X | X |
| ATM | A2893P | X | X | |
| ARID1AP | P703T | X | X | X |
| PTPRD | S1554R | X | X | |
| ARID2 | V1649L | X | X | X |
| EPHA3 | R447W | X | X | X |
| BLM | fmshift | X | X | X |
| RECQL4 | V1020M | X | X | |
| CARD11 | V659M | X | X | |
| RB1 | I517S | X | X | |
| NUP93 | I583M | X | X | X |
| HGF | A46V | X | X | |
| SMARCB1 | fmshift | X | X | |
| RAD52 | R396C | X | X | |
| FOXL2 | fmshift | X | X | |
| RAD 50 | I94T | X | ||
| PREX 2 | P963S | X | ||
| BCL2L2 | R161H | X | ||
| SNCAIP | R33Q | X |