Table 4.
Comparison of Effective Dose From 124I-PGN650 to Other Tracers Labeled With 124I and to Other Common Nuclear Medicine Radiopharmaceuticals.
| Tracer | Effective Dose, mSv/MBq |
|---|---|
| 124I-PGN650 (this work) | 0.41 |
| 124I-MIP-109520 | 0.58 |
| 124I-MIBG22 | 0.25 |
| 111In-F(ab′)2 29 | 0.20 |
| 111In-leukocytesC30 | 0.36 |
| 111In-pentetreotide29 | 0.054 |
| 67Ga-citrate29 | 0.10 |
| 64Cu-ATSM31 | 0.036 |
| 89Zr-trastuzumab32 | 0.61 |
| 64Cu-DOTA-trastuzumab33 | 0.036 |
| 18F-FDG30 | 0.019 |
Abbreviations: MIP-1095, (S)-2-(3-((S)-1-carboxy-5-(3-(4-[(124)I]iodophenyl)ureido)pentyl)ureido)pentanedioicacid, MIBG, metaiodobenzylguanidine, ASTM, diacetyl-bis(N4-methylthiosemicarbazone, DOTA, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid, FDG, fluorodeoxyglucose.