Table 2. Counts of monocyte subsets, monocyte subsets with PD-1 expression, and a percentage of PD-1+ cells within each monocyte subset in the blood samples from VLBW infants collected on the 5th DOL.
CL MO | IM MO | NC MO | p | |
---|---|---|---|---|
MO count (cell/μl); median [IQR] | 850 [463–1921] | 75 [35–134] | 41 [12–106] | p < 0.0001*, Post-hoc tests**: p < 0.0001 for CL MO vs. IM MO, p < 0.0001 for CL MO vs. NC MO, p = 0.0009 for IM MO vs. NC MO |
PD-1-positivecount (cell/μl); median[IQR] | 2 [0.2–5.42] | 8.5 [3–15] | 0.33 [0–2] | p < 0.0001*, Post-hoc tests**: p < 0.0001 for CL MO vs. IM MO, p = 0.0011 for CL MO vs. NC MO, p < 0.0001 for IM MO vs. NC MO |
PD-1-positive (%); median [IQR] | 0.29 [0.05–0.58] | 11.6 [6.34–22.6] | 1.53 [0.17–4.81] | p < 0.0001*, Post-hoc tests**: p < 0.0001 for CL MO vs. IM MO, p < 0.0001 for CL MO vs. NC MO, p < 0.0001 for IM MO vs. NC MO |
*—Kruskal—Wallis test,
**—nonparametric comparisons for each pair using Wilcoxon method
CL MO—classical monocytes, IM MO—intermediate monocytes, NC MO—non-classical monocytes