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. 2017 Oct 19;12(10):e0186702. doi: 10.1371/journal.pone.0186702

Table 5. Age, gender, ethnicity- adjusted and multivariate odds ratio of risk factor for the suspected NAFLD according to marijuana use in subjects with fasting data (NHANES 2005–2014, n = 6796).

Age, gender, ethnicity-adjusted Multivariate model 1 Multivariate model 2
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Marijuana use
Never 1 0.001* 1 0.012* 1 0.012*
Past user 0.83 (0.72–0.96) 0.011 0.84 (0.71–0.99) 0.040 0.87 (0.74–1.02) 0.089
Current user 0.71 (0.57–0.89) 0.004 0.73 (0.56–0.96) 0.025 0.72 (0.55–0.94) 0.015
Marijuana use
Never 1 0.001* 1 0.018* 1 0.016*
Past user 0.83 (0.72–0.96) 0.011 0.84 (0.71–0.99) 0.040 0.87 (0.74–1.02) 0.090
Current user
 light user 0.74 (0.53–1.02) 0.065 0.74 (0.51–1.08) 0.121 0.71 (0.49–1.02) 0.066
 Heavy user 0.69 (0.51–0.93) 0.015 0.73 (0.53–1.00) 0.052 0.72 (0.52–1.00) 0.049

Abbreviation: NAFLD, nonalcoholic fatty liver disease; NHANES, National Health and Nutrition Examination Survey; OR, odds ratio; CI, confidence interval. The multivariate model 1 was adjusted for age, gender, ethnicity, education level, economic status, body mass index, smoking status, alcohol consumption, diabetes, hypertension, total cholesterol, high-density lipoprotein cholesterol, fasting triglycerides, and current use of cocaine, heroin, and/or amphetamine. The multivariate model 2 includes HOMA index in addition to the variables addressed in model 1.

*P value for the test of trend of odds.