Table 5. Age, gender, ethnicity- adjusted and multivariate odds ratio of risk factor for the suspected NAFLD according to marijuana use in subjects with fasting data (NHANES 2005–2014, n = 6796).
Age, gender, ethnicity-adjusted | Multivariate model 1 | Multivariate model 2 | ||||
---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Marijuana use | ||||||
Never | 1 | 0.001* | 1 | 0.012* | 1 | 0.012* |
Past user | 0.83 (0.72–0.96) | 0.011 | 0.84 (0.71–0.99) | 0.040 | 0.87 (0.74–1.02) | 0.089 |
Current user | 0.71 (0.57–0.89) | 0.004 | 0.73 (0.56–0.96) | 0.025 | 0.72 (0.55–0.94) | 0.015 |
Marijuana use | ||||||
Never | 1 | 0.001* | 1 | 0.018* | 1 | 0.016* |
Past user | 0.83 (0.72–0.96) | 0.011 | 0.84 (0.71–0.99) | 0.040 | 0.87 (0.74–1.02) | 0.090 |
Current user | ||||||
light user | 0.74 (0.53–1.02) | 0.065 | 0.74 (0.51–1.08) | 0.121 | 0.71 (0.49–1.02) | 0.066 |
Heavy user | 0.69 (0.51–0.93) | 0.015 | 0.73 (0.53–1.00) | 0.052 | 0.72 (0.52–1.00) | 0.049 |
Abbreviation: NAFLD, nonalcoholic fatty liver disease; NHANES, National Health and Nutrition Examination Survey; OR, odds ratio; CI, confidence interval. The multivariate model 1 was adjusted for age, gender, ethnicity, education level, economic status, body mass index, smoking status, alcohol consumption, diabetes, hypertension, total cholesterol, high-density lipoprotein cholesterol, fasting triglycerides, and current use of cocaine, heroin, and/or amphetamine. The multivariate model 2 includes HOMA index in addition to the variables addressed in model 1.
*P value for the test of trend of odds.