Figure 3.

Food intake dictates the mode of division of proliferating cells in the crypt base. % of dividing cells that were asymmetrically or symmetrically dividing in mice fed ad libitum (Ad lib), fed 50% of their normal daily intake (50% fed), fasted (Fasted), and fasted for 12 h and then refed (Fast-Refed) in the duodenum (a), jejunum (b), ileum (c) and combined as the whole intestine (d). n = 8 mice per group, all dividing cells per 5 µm section was analyzed with a total of 30 µm from each segment of the intestine (duodenum, jejunum, ileum) per mouse. Values are mean ± SEM. % of asymmetric division data were analyzed using a one-way ANOVA. Tukey–Kramer post hoc analysis was performed. Means with different letters are significantly different. Means with different letters indicate significantly different, P < 0.05